Table 1.
Granule class | Granule components |
---|---|
Primary/azurophilic | Cathepsin G, BPI, lysozyme, elastase, myeloperoxidase (MPO), α-defensins |
Secondary/specific | Flavocytochrome b558, LL-37 (hCAP18), lysozyme, gelatinase, lactoferrin, CD11b/CD18 (CR3) |
Tertiary/gelatinase | Flavocytochrome b558, lysozyme, gelatinase, CD11b/CD18 (CR3) |
Proteins that have been shown to have or produce antimicrobial activity against Gc in vitro are bolded and italicized. Proteins to which Gc is resistant are indicated in red type.