Table 2.
Spared white matter after Tat-Bcl-xL and Tat-BH4 treatment.
Time after Injury |
Injury + Vehicle (n=3) |
Injury + Tat-Bcl-xL (n=3) |
Injury + Tat-BH4 (n=3) |
P | |
---|---|---|---|---|---|
Spared White matter * |
7 days | 0.230 ± 0.05 | 0.28±0.03 | 0.32±0.04 | 0.110 |
60 days | 0.291±0.12 | 0.32±0.15 | 0.248±0.06 | 0.068 |
White matter sparing was defined as tissue showing normal myelin appearance and density (lacking cyst, degeneration). To eliminate fixation –dependent artifacts in spinal cord cross-sectional area, spared myelin at the impact site was expressed relative to the area of white matter measured 1 cm rostral to the site of injury.