Skip to main content
. 2001 Apr 1;29(7):1399–1409. doi: 10.1093/nar/29.7.1399

Figure 3.

Figure 3

The RAG1 protein and its association to DNA. Top, the RAG1 core region has a trypsin-accessible site, which may divide it into two functional domains. Bottom, the RAG1 protein functions as a dimer, in association with RAG2 (not shown). The N-terminal region of RAG1 associates with the RSS conserved motifs. The C-terminal region associates with the coding DNA. A loop of DNA can be imagined (labeled spacer) that differs in length between the two RSS classes. The cis–trans relationships of protein and DNA are still not well-defined (see text).