Table 1.
Demographics of the cohort and univariate analysis for the association between maternal characteristics and pre-eclampsia
| Demographic | Pre-eclampsia (n=293) % |
Normal (n-3,423) % |
RR (95% CI) |
p-value |
|---|---|---|---|---|
| Maternal Age (yrs) | ||||
| <25 | 20 (6.8) | 99 (2.9) | 2.2 (1.5–3.3) | 0.002 |
| 25–34 | 95 (32.4) | 1,064 (31.1) | Reference | - |
| 35–39 | 144 (49.1) | 1,868 (54.6) | 0.8 (0.6–1.0) | 0.07 |
| ≥40 | 34 (11.6) | 392 (11.4) | 1.0 (0.7–1.4) | 0.93 |
| Maternal Race | ||||
| Caucasian | 214 (73.0) | 2,828 (82.6) | Reference | - |
| African American | 63 (21.5) | 283 (8.3) | 2.7 (2.1–3.4) | <0.001 |
| Asian | 4 (1.4) | 92 (2.7) | 0.5 (0.2–1.4) | 0.17 |
| Hispanic | 1 (0.3) | 56 (1.6) | 0.2 (0.0–1.5) | 0.08 |
| Other | 11 (3.7) | 164 (4.8) | 0.9 (0.4–1.7) | 0.70 |
| Chronic HTN | 47 (16.0) | 121 (3.5) | 3.9 (3.0–5.2) | <0.001 |
| Pre-gestational DM | 28 (9.5) | 66 (1.9) | 4.0 (2.9–5.6) | <0.001 |
| Tobacco Use | 21 (7.2) | 182 (5.3) | 1.3 (0.9–2.0) | 0.19 |
| Alcohol Use | 60 (20.4) | 768 (22.4) | 0.9 (0.7–1.1) | 0.35 |
| Illicit Drug Use | 7 (2.4) | 21 (0.6) | 3.1 (1.6–6.0) | 0.009 |
| Maternal BMI (kg/m2) | ||||
| <18.5 | 3 (1.0) | 87 (2.5) | 0.4 (0.1–1.3) | 0.11 |
| 18.5–24.9 | 72 (24.6) | 1666 (48.7) | Reference | - |
| 25–29.9 | 78 (26.6) | 742 (21.7) | 1.3 (1.0–1.7) | 0.04 |
| ≥30 | 108 (36.9) | 581 (17.0) | 2.7 (2.1–3.4) | <0.001 |
| Unknown* | 32 (10.9) | 347 (10.1) | 1.1 (0.7–1.5) | 0.67 |
HTN=hypertension; DM=diabetes mellitus; BMI=body mass index; RR=relative risk; CI=confidence interval
*
Indicates patients for which either height, weight, or both were missing from patient questionnaire