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. 2011 May 14;286(27):23982–23995. doi: 10.1074/jbc.M111.220491

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — PPARγ-dependent induction of chemerin expression by rosiglitazone in BMSCs. PPARγ activation by rosiglitazone (1 μm) induced a time-dependent increase of chemerin protein secretion as assessed by immunoblotting analysis (A). Knockdown (KD) of PPARγ expression abrogated the induction of chemerin and CD36 mRNA levels as assessed by qPCR analysis in BMSCs in response to rosiglitazone (ROSI) treatment (B). Error bars represent S.E. (n = 4) and are expressed relative to the VEH control. *, p < 0.05 versus VEH. LZ, LacZ.