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. 2011 May 12;286(27):24023–24035. doi: 10.1074/jbc.M111.224600

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 7. — Biological processes affected by effectors analyzed in this study. S. typhimurium effectors binding to host cell targets suggest a set of biological contexts to be influenced by infection. SseG (G) and SspH2 (H2) bind, respectively, to Caprin-1 and Bub3/AH receptor-interacting protein (AIP)/Sgt-1, host proteins influencing cell cycle control. SseF (F), SseG, SseL (L), and SseJ (J) target proteins located at desmosomes or focal adhesions, suggesting a role in the regulation of cell attachment. SspH1 (H1), SspH2, and SseL target PKN1, Sgt1, and OSBP, respectively, arguing for a possible role in the regulation of innate immunity.