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TRα1 and TRβ contribute to skin proliferative responses. Epidermal thickness (left) and BrdU incorporation (right) were determined in WT mice, double knock-out mice (KO), and single knock-out mice lacking either TRα1 (KOα) or TRβ (KOα) 4 days after the start of treatment with vehicle or TPA. Data are shown as mean values ± S.D. (error bars). *, p < 0.05; **, p < 0.01; ***, p < 0.001 versus WT animals.
