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. 2011 May 19;286(27):24275–24287. doi: 10.1074/jbc.M111.229922

TABLE 2.

Antibacterial, hemolytic, and cytotoxic activities of selected cliotides

Peptide MICa
HD50b IC50c
E. coli K. pneumonia P. aeruginosa
μm
cT1 1.1 2.7 4.7 7.1 0.6
cT2 >100 >100 >100 >100 8.0
cT3 >100 >100 >100 13.1 2.0
cT4 1.0 5.5 7.5 8.4 0.6
D4Rd 1.3 1.9 1.5
Melittine 3.2

a MIC, minimal inhibitory concentration.

b HD50 refers to the peptide concentration that causes 50% lysis of red blood cells.

c IC50 refers to the peptide concentration that causes 50% death of HeLa cells.

d D4R is a synthetic antibacterial peptide that was used as the positive control for antibacterial assay.

e Melittin was used as the positive control for hemolytic assay.