TABLE 2.
Peptide | MICa |
HD50b | IC50c | ||
---|---|---|---|---|---|
E. coli | K. pneumonia | P. aeruginosa | |||
μm | |||||
cT1 | 1.1 | 2.7 | 4.7 | 7.1 | 0.6 |
cT2 | >100 | >100 | >100 | >100 | 8.0 |
cT3 | >100 | >100 | >100 | 13.1 | 2.0 |
cT4 | 1.0 | 5.5 | 7.5 | 8.4 | 0.6 |
D4Rd | 1.3 | 1.9 | 1.5 | ||
Melittine | 3.2 |
a MIC, minimal inhibitory concentration.
b HD50 refers to the peptide concentration that causes 50% lysis of red blood cells.
c IC50 refers to the peptide concentration that causes 50% death of HeLa cells.
d D4R is a synthetic antibacterial peptide that was used as the positive control for antibacterial assay.
e Melittin was used as the positive control for hemolytic assay.