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Surface representations of the complexes of wild-type enzyme with DEQ (A) and SAN (B) and of the mutant W275G with the same inhibitors DEQ (C) and SAN (D). The protein surface is green with hydrophobic patches shown as yellow surface and yellow stick models of the corresponding residues. The inhibitors are shown in magenta (DEQ) and orange (SAN). The 2Fo − Fc omit map is contoured at 1 σ.
