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. 2011 Jul;13(7):725–735. doi: 10.1093/neuonc/nor053

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© The Author(s) 2011. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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Fig. 5. — Effects of CHOP/GADD153 siRNA on cell viability, apoptosis, and autophagy after ATO treatment. Bar graphs showing a significant increase in cell viability after GADD153 silencing in U87 (A) and T98G (B) HGG cells (left panel). A significant decrease in apoptotic (middle panel) and autophagic (right panel) rate was also seen. Data are shown as mean ± SD of 3 independent experiments. Viability data are shown as normalized to DMSO (no ATO treatment); *P < .05, Student's t-test compared with control siRNA.