Figure 2.
Myocardial hypertrophy is accompanied by increased cardiac stress. (A) Caspase-3 activity was measured in hearts from mice treated for 7 d with either T3 or ISO compared to PBS as negative controls, with fluorescence generated by caspase-3 activity (arbitrary fluorescence units). (B) Hydrogen peroxide was measured using a fluorescence-based assay. (C) Levels of malonaldehyde (MDA) as an indicator of lipid peroxidation were measured by spectrophotometry. For all graphs, results represent mean + SE (N = 5 mice per group) with means compared using a student's t test, *p < 0.05.