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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Ultrasound Med Biol. 2011 Jun 8;37(8):1259–1270. doi: 10.1016/j.ultrasmedbio.2011.04.019

Figure 6.

Figure 6

Left: Number of sonicated locations where extensive erythrocyte extravasation was observed as a function of peak negative pressure amplitude. The threshold for extensive extravasation appeared at a lower exposure level with ketamine/xylazine compared to isoflurane/oxygen. Right: MRI contrast enhancement for locations with and without extensive erythrocyte extravasation (mean ± standard deviation shown). In both cases, sonication with ketamine/xylazine (left bars) resulted in significantly more enhancement (*P<0.05).