Skip to main content
. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Mol Carcinog. 2011 Mar 22;50(8):614–624. doi: 10.1002/mc.20760

Figure 6.

Figure 6

ER-α was largely dispensable for WA-induced G2/M phase cell cycle arrest. (A) Representative flow histograms depicting cell cycle distribution in MDA-MB-231 cells stably transfected with empty pIRES vector (pIRES-empty) or pIRES vector encoding for ER-α (pIRES-ER-α) and treated for 24 h with DMSO or 2.5 μM WA. (B) Cell cycle distribution in pIRES-empty and pIRES-ER-α cells after 24 h treatment with DMSO or 2.5 μM WA. Results shown are mean ± SD (n= 3). Significantly different (P < 0.05) compared with (a) respective DMSO-treated control for each cell line and (b) between WA-treated pIRES-empty cells and WA-treated pIRES-ER-α cells by one-way ANOVA followed by Bonferroni's test.