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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Thromb Haemost. 2011 Jul;9(7):1308–1317. doi: 10.1111/j.1538-7836.2011.04331.x

Figure 2.

Figure 2

APC stimulates AMPK activation. (A) In vivo regional ischemia stimulates phosphorylation of AMPK as shown by immunoblots. Values are means ± S.E., n=3. *p<0.05 vs. Sham. (B) Both APC and 2Cys but not E170A trigger AMPK and ACC phosphorylation during reperfusion. (C) and (D) Activation of AMPKα1 and AMPKα2 in the same heart samples as assessed by a kinase assay. Values are means ± S.E., n=4–6. *p<0.05 vs. Sham saline; †p<0.05 vs. I/R saline.