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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2011 May 24;1808(9):2156–2166. doi: 10.1016/j.bbamem.2011.04.020

Figure 6.

Figure 6

(a) Cytotoxicity (in mouse L-cells) of CMVL–DNA complexes and other vectors at ΦDOPC = 0. Cell viability is plotted as a function of lipid/DNA weight ratio (L/D). (b) Cytotoxicity of CMVL–DNA complexes and other vectors for optimal or near-optimal (for CMVL2 and CMVL3) formulation (ΦDOPC = 0.4 for MVL5 and the CMVLs; ΦDOPC = 0 for DOTAP and Lipofectamine 2000). Cell viability is plotted as a function of total lipid/DNA weight ratio (TL/D; for DOTAP and Lipofectamine 2000, L/D = TL/D). Note the change in scale for the x-axis. For both plots, error bars show the standard deviation of quadruplicate measurements.