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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Gastroenterology. 2011 Apr 12;141(1):338–347. doi: 10.1053/j.gastro.2011.04.001

Figure 1. AC-DILI genome-wide association results.

Figure 1

Each point represents association analysis results for a single SNP with chromosome position on the x axis and -log10 p-value on the y axis. All 201 DILI cases and 532 population controls were included in the analysis. SNPs with p-values smaller than 10−6 and 10−7 are highlighted in green and red, respectively. Panel A shows the results for the entire genome. Panels B to D show enlarged sections of the MHC region. Panel B is an enlargement of the results presented in A, panel C shows the analysis of each SNP in this chromosome region conditioned on the top class II SNP (rs9274407) and panel D analysis of each SNP conditioned on the top class I and II SNPs (rs9274407 and rs2523822). Positions of a range of MHC genes are shown in B to D.