Skip to main content
. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Pharmacol Biochem Behav. 2011 May 23;99(3):311–315. doi: 10.1016/j.pbb.2011.05.015

Figure 1.

Figure 1

Generalization of 5-MeO-DMT to bufotenine and acetylbufotenine in WT and Tg-CYP2D6 mice. Tests of generalization of 5-MeO-DMT to bufotenine [WT: triangle; TG: circle] and acetylbufotenine [WT: square; TG: hexagon] in mice trained with 5-MeO-DMT [0.3 mg/kg, 15 min] as a discriminative stimulus. Each point represents the mean of one determination in each of 5 WT or 6 TG mice. The asterisk indicates a significant difference from both training conditions. Values given at the points labeled V and TD in the upper and lower panels are for the training conditions, vehicle and 0.3 mg/kg 5-MeO-DMT, respectively. The triangle and the circle refer to WT and TG mice, respectively. Ordinate: upper panel: percent 5-MeO-DMT-appropriate responding; lower panel: rate expressed as responses per minute. Abscissa: dose plotted on a log scale.