Table 1.
Factor | Type | Group | Maximum risk to average ratio |
Smoking | Exogenous | Behavioral | 3 |
Alcohol | Exogenous | Behavioral | Non-significant |
Diet/obesity | Exogenous | Behavioral | 1.72 |
Occupational hazard | Exogenous | Environmental | - |
Radiation | Exogenous | Environmental | Inconclusive |
Age | Endogenous | Biological | - |
Race | Endogenous | Biological/behavioral/environmental | 1.4 |
Family history | Endogenous | Genetic | 32 |
Peutz-Jeghers syndrome | Endogenous | Genetic | 132 |
FAMMM syndrome | Endogenous | Genetic | 13.1 |
HNPCC | Endogenous | Genetic | 7 |
Hereditary pancreatitis | Endogenous | Genetic | 60 |
Chronic pancreatitis | Endogenous | Behavioral | 26.3 |
Diabetes mellitus | Endogenous | Biological/environmental | 2.0 |
Hormonal | Endogenous | Biological | Inconclusive |
Allergy | Endogenous | Biological | Non-significant |
FAMMM: Familial atypical multiple mole melanoma; HNPCC: Hereditary non-polyposis colorectal carcinoma syndrome.