Table 8.

Memory required by each software to map 1 million 35 base reads to human reference genome. The memory requirement increases with the number of reads and/or the read length; this increase is typically linear with the increase in the number of base pairs in the dataset

Mapper	Memory usage (GB)
drFAST-DP	1.3
drFAST-CT	1.3
BFAST	≥10
Bowtie	4.5
SHRiMP	16
SOCS	≥5a
PerM	2
Mapread	≥8b

^aWe set the memory usage of SOCS to 5 GB.

^bWe set the memory usage of Mapreads to 8 GB.