Figure 6.
Effect of Ad5/6GL in C57Bl/6 mice and Syrian hamsters. 1 × 1010 virus particles (vp) of Ad5GL or Ad5/6GL was injected intravenously into C57BL/6 mice and intrajugularly into Syrian hamsters. (a) Mice were imaged for luciferase expression after 24 hours for 3 minutes at 2 × 2 binning (N = 10). (b,c) Hamsters were imaged after 4 days for 10 minutes at 2 × 2 binning (N = 4). Shown are (c) white light images overlaid with luciferase expression in pseudo-color from 688 to 1400 gray values and (b) quantification of luciferase expression. *P = 0.05; ns = not significant. Means ± SEM.