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. Author manuscript; available in PMC: 2011 Jul 5.
Published in final edited form as: Ann Neurol. 2010 May;67(5):639–647. doi: 10.1002/ana.21947

FIGURE 4.

FIGURE 4

Time-course of L-dopa treatment effects. PITx3(−/−) mice were given L-dopa or saline injections at different time points (1 hour, 6 hours, or 12 hours) before training for 3 days. (A) Latency to fall in each trial. (B) Average latency to fall during each session (n = 6 per treatment). (C) Dopamine (DA) content in dorsal striatum of L-dopa–naive PITx3(−/−) animals, PITx3(−/−) animals receiving an acute L-dopa injection (1 hour prior to sample collection), and PITx3(−/−) animals receiving chronic L-dopa treatment for 7 days and treatment cessation for either 3 or 10 days. n = 6 per treatment.