Table 1.

Genome alterations reported in published whole genome studies

Tumor type	Number of tumors sequenced	Approximate number of point mutations per tumor	Average number of non-synonymous mutations per tumor	Number of rearrangements per tumor	Reference(s)
Lung (non-small-cell)	1	50,000	302	43	Lee et al. (2010) [8]
Melanoma	1	30,000	187	74	Pleasance et al. (2010) [2]
Lung (small-cell)	1	20,000	94	58	Pleasance et al. (2010) [3]
Breast	2	6,000	~30	40	Ding et al. (2010) [4]; Shah et al. (2009) [9]
Prostate	7	4,000	20	~100	Berger et al. (2011) [1]
AML	1	1,000	8	ND	Mardis et al. (2009) [5]

AML, acute myelogenous leukemia; ND, not determined.