FIGURE 2.
β2GPI levels are lower in anti-Ro60 exposed neonates with cardiac NL compared to non-cardiac NL. (A) β2GPI concentration, measured by ELISA, in umbilical cord blood from children affected by cardiac NL (n=53) and non-cardiac NL controls (n=44). Solid horizontal lines represent mean β2GPI concentration. Dashed lines connect β2GPI levels in umbilical cord blood from twins discordant for cardiac NL. (B) Immunoblot analysis of a panel of 9 umbilical cord blood samples (4 non-cardiac NL and 5 cardiac NL) probed with anti-β2GPI antibody were quantitatively consistent with those measured by ELISA.