Table I.
Clinical and demographic characteristics of anti-Ro60 exposed neonates with cardiac NL compared to those without cardiac NL
| Cardiac NL* (N=53) |
Non-Cardiac NL** (N=44) |
p Value | |
|---|---|---|---|
| Sex of Child | 0.22 | ||
| Male | 24 (45%) | 25 (57%) | |
| Female | 29 (55%) | 17 (39%) | |
| NA | 0 (0%) | 2 (4%) | |
| Race/ethnicity | 0.78 | ||
| White | 43 (81%) | 36 (82%) | |
| Black | 3 (6%) | 3 (7%) | |
| Hispanic | 1 (2%) | 4 (9%) | |
| Asian | 4 (7%) | 1 (2%) | |
| Other/NA | 2 (4%) | 0 (0%) | |
| Antibody Status | 0.68 | ||
| Anti-Ro+/La+ | 29 (55%) | 27 (61%) | |
| Anti-Ro+/La− | 24 (45%) | 17 (39%) | |
| Medication | |||
| Dexamethasone | 26 (49%) | 3 (7%) | 0.0001 |
| Delivery | |||
| C-section | 37 (70%) | 10 (23%) | 0.0001 |
| Vaginal | 3 (6%) | 16 (36%) | |
| NA | 13 (24%) | 18 (41%) | |
| Birth Weight (g) | 2682 (±647)+ | 3124 (±572)++ | 0.007 |
| Gestational age(weeks) | 37 (±2)# | 38 (±2)## | 0.018 |
*
3rd degree block (n=47), 2nd degree (n=2), cardiomyopathy (n=3), sinus bradycardia (n=1)
**
rash (n=5), liver complications (n=1)
+
n=36,
++
n=29,
#
n=44,
##
n=31
Birth weight and gestational age are presented as mean±SD. All other data are reported as N (%). NL, neonatal lupus.