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. 2011 Mar 29;3(2):1732–1743. doi: 10.3390/cancers3021732

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© 2011 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 3. — Aberrant methylation of NIS detected by methylation-specific PCR (MSP). Lanes 1 and 2: universal methylated and unmethylated controls. Lanes 3-14 span biopsies for Cases 3, 4 and 13. Note presence of methylated product in lanes 3, 7 and 9. Note absence of methylated product in lanes 5, 11 and 13. Lanes 15 and 16: negative control. (A1T – block A1 tumor, A6N – block A6 normal, B5Met – block B5 metastasis, Case4-N – normal thyroid, A5T – block A5 tumor, A9N – block A9 normal).