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. 2010 Feb 10;30(6):2138–2149. doi: 10.1523/JNEUROSCI.5752-09.2010

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Copyright © 2010 the authors 0270-6474/10/302138-12$15.00/0

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Figure 6. — Effect of reduction of GRK2 in GFAP-positive astrocytes on carrageenan- and CCL3-induced hyperalgesia. a, GRK2 protein levels in microglia (n = 4) and astrocytes (n = 4) of GFAP-GRK2^f/+ and control GFAP-GRK2^+/+ mice. The inset depicts Western blots for GRK2 protein and β-actin as a loading control. b, Percentage decrease in heat withdrawal latency after intraplantar carrageenan injection in GFAP-GRK2^+/+ (n = 8) and GFAP-GRK2^f/+ mice (n = 8). c, Percentage decrease in heat withdrawal latency after intraplantar CCL3 injection in GFAP-GRK2^+/+ (n = 16) and GFAP-GRK2^f/+ (n = 16). Data are expressed as mean ± SEM.