Fig. 2.

sda motoneurons are exposed to increased synaptic excitation. A and B: typical examples of spontaneous rhythmic currents (SRCs) recorded in aCC/RP2 motoneurons (traces are from a RP2 motoneuron in this instance) in WT and sda L3. Scale bars = 200 pA/2 s. C: the mean amplitude of SRCs recorded was significantly greater in sda motoneurons (55.6 ± 3.2 vs. 68.9 ± 5.4pA/pF). D: the duration of SRCs was also significantly increased in sda motoneurons (1.79 ± 0.3 vs. 2.7 ± 0.2 s). E: the frequency of SRCs observed was significantly reduced in sda motoneurons (14.4 ± 2.1 vs. 6.0 ± 1.4 min⁻¹). For all means, n ≥ 8. F and G: cumulative probability plots that better show the distribution of individual current amplitudes (F) and duration (G) for the averaged WT and sda data shown in C and D, respectively.