Table 2.

Areas of activation emerging from the comparison of social exclusion and fair play during Cyberball.

Brain region	X	Y	Z	Size	t	p
Social exclusion > fair play
TD
Right posterior insula	42	−13	10	8846	4.59	0.000181
Right PCC	9	−52	7	2202	4.27	0.000371
Left PCC/PHG	−9	−58	7	10,005	5.01	0.000066
Ventral ACC	−12	41	7	1841	3.33	0.003328
Left vlPFC	−51	18	−8	2040	3.66	0.001573
Left anterior STS	−45	−7	−8	2807	4.79	0.000111
Left posterior insula	−45	−22	13	8275	4.90	0.000086
ASD
Left retrosplenial cortex	−9	−34	4	2701	5.45	0.000068
Left superior precentral gyrus	−54	−13	40	1430	3.58	0.002731
Left inferior precentral gyrus	−57	−7	10	1387	3.65	0.002392
Fair play > social exclusion
TD
Left cerebellum	−42	−40	−38	1939	−3.49	0.002282
Parietal cortex	27	−58	58	26,296	−4.96	0.000075
Right precentral gyrus	39	−1	61	5739	−3.82	0.00108
ASD
Right parietal cortex	36	−46	49	10,895	−5.62	0.000049
Right MFG	33	29	28	5069	−4.59	0.000356
Right anterior insula	33	23	7	1475	−4.22	0.000742
Right vlPFC	36	44	25	1108	−3.04	0.008249
Right precentral gyrus	21	8	61	1289	−4.74	0.000262
Right dmPFC	15	53	25	1156	−3.82	0.001665
Left vlPFC	−21	53	4	2266	−3.51	0.003131
Left parietal cortex	−33	−49	28	2648	−3.75	0.001941
Left cerebellum	−39	−37	−35	1903	−3.96	0.001265

Regions identified in a full brain contrast of social exclusion to fair play within each group (TD and ASD). Talairach coordinates and statistics refer to the voxel with the maximum signal change in each region of interest. Abbreviations: posterior cingulate cortex (PCC), parahippocampal gyrus (PHG), anterior cingulate cortex (ACC), ventrolateral prefrontal cortex (vlPFC), middle frontal gyrus (MFG), dorsomedial prefrontal cortex (dmPFC), superior temporal sulcus (STS).