Table 3.
Areas of activation emerging from the comparison of rule violation and fair play during Cybershape.
| Brain region | X | Y | Z | Size | t | p |
|---|---|---|---|---|---|---|
| Rule violation > fair play | ||||||
| TD | ||||||
| Right MTG | 60 | −46 | −2 | 3947 | 4.96 | 0.000102 |
| Right parietal cortex | 39 | −46 | 52 | 6501 | 5.01 | 0.000091 |
| Left parietal cortex | −39 | −70 | 40 | 3984 | 4.92 | 0.000111 |
| Bilateral orbitofrontal cortex | −18 | 59 | 1 | 23,543 | 5.25 | 0.000055 |
| Right anterior ITS | 48 | −1 | −26 | 1700 | 3.71 | 0.001587 |
| Right dlPFC | 33 | 11 | 46 | 2258 | 3.61 | 0.001985 |
| Left dlPFC | −30 | 14 | 40 | 3540 | 4.49 | 0.000285 |
| Dorsomedial PFC | 3 | 29 | 46 | 7204 | 4.22 | 0.000512 |
| ASD | ||||||
| Right supramarginal gyrus | 45 | −43 | 52 | 10,622 | 4.87 | 0.000092 |
| Right STS | 57 | −19 | −5 | 1303 | 3.61 | 0.001741 |
| Right cerebellum | 33 | −76 | −35 | 6292 | 4.48 | 0.000229 |
| Right MOG | 39 | −82 | 16 | 1278 | 3.76 | 0.001235 |
| Right caudate | 12 | 2 | 7 | 2017 | 4.88 | 0.000091 |
| Cuneus | −6 | −55 | 37 | 4866 | 4.49 | 0.000224 |
| Left caudate | −15 | −4 | 7 | 1900 | 4.13 | 0.000516 |
| Left SMG/STS | −45 | −43 | 28 | 22,574 | 5.16 | 0.000048 |
| Right insula | 39 | 20 | 13 | 7117 | 4.44 | 0.000252 |
| Left insula | −36 | 20 | −5 | 7409 | 5.40 | 0.000027 |
| Dorsomedial and dorsolateral PFC | 36 | 8 | 49 | 98,004 | 6.76 | 0.000001 |
| Fair play > rule violation | ||||||
| TD | ||||||
| Right cerebellum | 21 | −22 | −23 | 1671 | −4.58 | 0.000234 |
| Right posterior insula | 33 | −16 | 25 | 1633 | −4.19 | 0.000545 |
| Right paracentral lobule | 18 | −46 | 52 | 1307 | −3.68 | 0.001706 |
| Cerebellar vermis | 3 | −49 | −11 | 3927 | −5.50 | 0.000032 |
| Pons | −9 | −16 | −35 | 2126 | −4.37 | 0.000366 |
| Left cuneus | −15 | −76 | 13 | 1790 | −3.81 | 0.001294 |
| Left precentral gyrus | −36 | −25 | 52 | 2596 | −3.68 | 0.001726 |
| Right insula | 39 | −4 | 4 | 3306 | −4.46 | 0.000304 |
| Right PCC | 21 | −46 | 13 | 3147 | −4.54 | 0.000253 |
| Right hippocampus | 30 | −31 | 10 | 3830 | −4.02 | 0.000806 |
| Left insula | −27 | −4 | 19 | 5147 | −4.00 | 0.000839 |
| Left hippocampus | −33 | −34 | −5 | 4922 | −5.04 | 0.000085 |
| Left retrosplenial cortex | −15 | −43 | 4 | 3820 | −4.9792 | 0.000097 |
| Dorsal ACC/left paracentral lobule | −15 | −16 | 28 | 2913 | −4.00 | 0.00084 |
| ASD | ||||||
| Subgenual ACC | 3 | 14 | 1 | 2262 | −4.30 | 0.00035 |
| Ventral ACC | −6 | 38 | −2 | 1618 | −3.44 | 0.002613 |
| Left anterior MTG | −63 | −7 | −11 | 1046 | −4.06 | 0.000614 |
| Bilateral paracentral lobule | 9 | −25 | 58 | 8697 | −5.94 | 0.000008 |
| Right posterior insula | 39 | −10 | 22 | 1233 | −3.50 | 0.002251 |
| Right PCC/Hp | 18 | −37 | 13 | 7664 | −6.24 | 0.000004 |
| Left Hp | −36 | −25 | −8 | 6060 | −5.33 | 0.000033 |
| Left PCC | −24 | −31 | 7 | 5816 | −4.70 | 0.000136 |
Regions identified in a full brain contrast of rule violation to fair play within each group (TD and ASD). Talairach coordinates and statistics refer to the voxel with the maximum signal change in each region of interest. Abbreviations: posterior cingulate cortex (PCC), anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (dlPFC), prefrontal cortex (PFC), middle temporal gyrus (MTG), inferior temporal sulcus (ITS), superior temporal sulcus (STS), middle occipital gyrus (MOG), supramarginal gyrus (SMG), hippocampus (Hp).