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. 2011 Feb 25;1(3):280–294. doi: 10.1016/j.dcn.2011.02.002

Table 3.

Areas of activation emerging from the comparison of rule violation and fair play during Cybershape.

Brain region X Y Z Size t p
Rule violation > fair play
TD
Right MTG 60 −46 −2 3947 4.96 0.000102
Right parietal cortex 39 −46 52 6501 5.01 0.000091
Left parietal cortex −39 −70 40 3984 4.92 0.000111
Bilateral orbitofrontal cortex −18 59 1 23,543 5.25 0.000055
Right anterior ITS 48 −1 −26 1700 3.71 0.001587
Right dlPFC 33 11 46 2258 3.61 0.001985
Left dlPFC −30 14 40 3540 4.49 0.000285
Dorsomedial PFC 3 29 46 7204 4.22 0.000512
ASD
Right supramarginal gyrus 45 −43 52 10,622 4.87 0.000092
Right STS 57 −19 −5 1303 3.61 0.001741
Right cerebellum 33 −76 −35 6292 4.48 0.000229
Right MOG 39 −82 16 1278 3.76 0.001235
Right caudate 12 2 7 2017 4.88 0.000091
Cuneus −6 −55 37 4866 4.49 0.000224
Left caudate −15 −4 7 1900 4.13 0.000516
Left SMG/STS −45 −43 28 22,574 5.16 0.000048
Right insula 39 20 13 7117 4.44 0.000252
Left insula −36 20 −5 7409 5.40 0.000027
Dorsomedial and dorsolateral PFC 36 8 49 98,004 6.76 0.000001
Fair play > rule violation
TD
Right cerebellum 21 −22 −23 1671 −4.58 0.000234
Right posterior insula 33 −16 25 1633 −4.19 0.000545
Right paracentral lobule 18 −46 52 1307 −3.68 0.001706
Cerebellar vermis 3 −49 −11 3927 −5.50 0.000032
Pons −9 −16 −35 2126 −4.37 0.000366
Left cuneus −15 −76 13 1790 −3.81 0.001294
Left precentral gyrus −36 −25 52 2596 −3.68 0.001726
Right insula 39 −4 4 3306 −4.46 0.000304
Right PCC 21 −46 13 3147 −4.54 0.000253
Right hippocampus 30 −31 10 3830 −4.02 0.000806
Left insula −27 −4 19 5147 −4.00 0.000839
Left hippocampus −33 −34 −5 4922 −5.04 0.000085
Left retrosplenial cortex −15 −43 4 3820 −4.9792 0.000097
Dorsal ACC/left paracentral lobule −15 −16 28 2913 −4.00 0.00084
ASD
Subgenual ACC 3 14 1 2262 −4.30 0.00035
Ventral ACC −6 38 −2 1618 −3.44 0.002613
Left anterior MTG −63 −7 −11 1046 −4.06 0.000614
Bilateral paracentral lobule 9 −25 58 8697 −5.94 0.000008
Right posterior insula 39 −10 22 1233 −3.50 0.002251
Right PCC/Hp 18 −37 13 7664 −6.24 0.000004
Left Hp −36 −25 −8 6060 −5.33 0.000033
Left PCC −24 −31 7 5816 −4.70 0.000136

Regions identified in a full brain contrast of rule violation to fair play within each group (TD and ASD). Talairach coordinates and statistics refer to the voxel with the maximum signal change in each region of interest. Abbreviations: posterior cingulate cortex (PCC), anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (dlPFC), prefrontal cortex (PFC), middle temporal gyrus (MTG), inferior temporal sulcus (ITS), superior temporal sulcus (STS), middle occipital gyrus (MOG), supramarginal gyrus (SMG), hippocampus (Hp).