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Anterograde transport of glial-derived neurotrophic factor (GDNF) from putamen to globus pallidus. GDNF (brown) distribution at the center of the infusion (a) is confined to the putamen (Pu). Anterograde transport into external globus pallidus (GPe) and internal globus pallidus (GPi) is evident at distances of (b) 200-µm and (c) 240-µm posterior to the infusion. Second order neurons are seen to express GDNF in GPi (d, ×10 magnification of the area indicated by the arrowhead in c).
