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Relationship between B5R expression and oncolytic activity. (a) Schematic representation of the recombinant vaccinia virus LC16m8Δ-B5R. (b) Human cell lines were infected with B5R-positive or B5R-negative viruses at a multiplicity of infection of 0.5. The cell viabilities were determined 120 hours postinfection and are expressed as percentages of the cell survival of mock-infected cultures. The data are presented as mean + SD (n = 3).
