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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Stroke. 2011 May 5;42(7):2033–2044. doi: 10.1161/STROKEAHA.110.601369

Figure 6. PI3Kγ deficiency reduces MMP-9 activity and protein content.

Figure 6

Figure 6

A, Gelatin zymogram. Note that MMP-9 (92 and 82 kDa) and MMP-2 (63 kDa) bands were detected in the homogenates of ischemic (left, L) and contralateral (right, R) cortex 24 h after tMCAO. The region of interest is shown in adjoining coronal section. B, Densitometric analysis of the bands shown in A. Data represent mean ± s.d. from 3 separate experiments. *P<0.05 versus WT (saline-treated) control. C. ELISA assay of MMP-9 protein in ischemic (left) and contralateral (right) cortex (region of interest shown in adjoining coronal section) 24 h after tMCAO. n=5 for each group. **P<0.01 versus WT control.