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. 2011 Mar 23;301(1):C126–C136. doi: 10.1152/ajpcell.00311.2010

Fig. 7.

Fig. 7.

Hyperosmolar inhibition of ileal NHE3 activity occurs similarly in WT and NHERF2−/− ileum. Fifty millimolar mannitol was added only to the final Na buffer in studies measuring ileal NHE3 activity (see experimental procedures). Basal NHE3 activity and effect of mannitol are shown as means ± SE in WT (n = 10) and NHERF2−/− (n = 10) ileum. Hyperosmolarity significantly inhibited NHE3 activity in both WT and NHERF2−/− ileum. P values represent comparison of effect of hyperosmolarity in WT and NHERF2 ileum by one-way ANOVA.