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. 2011 Apr 20;301(1):F171–F178. doi: 10.1152/ajprenal.00339.2010

Fig. 1.

Fig. 1.

Renal cell apoptosis following unilateral ureteral obstruction (UUO). A: renal cortical histone-associated DNA fragment accumulation (ELISA) in wild-type (WT) and IL-18-binding protein transgenic (IL-18BP Tg) mice exposed to sham operation or 1 or 2 wk of UUO. B: graph depicting the number of apoptotic nuclei (TdT-mediated dUTP nick end labeling) per high-powered field (×400) in each treatment group. C: photographs (×400) depicting apoptotic nuclei (ApopTag) in renal cortical tissue sections counterstained with hematoxylin and eosin from WT and IL-18BP Tg mice exposed to sham operation or 1 or 2 wk of UUO. Apoptotic nuclei are stained brown and identified with black arrows.