Fig. 1.
Effect of 24-h treatment of embryonic day 19 fetal rat lung explants with nicotine,, or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), or 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal (NNA) (1 × 10−11, 1 × 10−8, and 1 × 10−5 M) on choline incorporation into disaturated phosphatidylcholine (A) and triolein uptake (B). There were significant dose-dependent increases in both choline incorporation and triolein uptake by nicotine, NNK, and NNA treatment (*P < 0.05 vs. control; n = 6).