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. 2011 Apr 8;301(1):L1–L8. doi: 10.1152/ajplung.00393.2010

Fig. 3.

Fig. 3.

Effect of 24-h treatment of embryonic day 19 fetal rat lung explants with nicotine, NNK, or NNA (1 × 10−11, 1 × 10−8, and 1 × 10−5 M) on peroxisome proliferator-activated receptor-γ (PPAR-γ) (A), fibronectin (B), and calponin (C) protein levels. PPAR-γ levels decreased significantly with nicotine (1 × 10−11, 1 × 10−8, and 1 × 10−5 M), NNK(1 × 10−8, and 1 × 10−5 M) and NNA (1 × 10−5 M). In contrast, fibronectin and calponin levels increased with nicotine, NNK, and NNA (*P < 0.05 vs. control; n = 3).