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Systolic function as represented by fractional shortening following in 1-, 3-, or 5-day tamoxifen (TAM) treatment in animals expressing Myh6-MerCreMer (Cre+) or non-Cre (Cre−) mice. Day 0 is the average of the 2 baseline measurements and days 2, 4, 6, 8, and 10 represent days following the start of TAM administration. *P < 0.05 vs. Cre−/5-day mice.
