Fig. 8.

Cardiac histology from Cre⁺/5-day and Cre⁻/5-day mice at day 6 and day 10 post-TAM treatment. A, D, and G: hemotoxylin and eosin (H&E) staining at ×200 in untreated Cre⁻ (A); Cre⁺/5-day, day 6 (D); and Cre⁺/5-day, day 10 (G). B, E, and H: periodic acid-Schiff (PAS) staining at ×200 in untreated Cre⁻ (B); Cre⁺/5-day, day 6 (E); and Cre⁺/5-day, day 10 (H). C, F, and I: picrosirius red (PSR) staining at ×200 in untreated Cre⁻ (C); Cre⁺/5-day, day 6 (F); and Cre⁺/5-day, day 10 (I). H&E staining reveals inflammatory cells seen on day 6 (‡) and condensed nuclear chromatin noted at Systolic function recovery (*). At day 10, intracellular staining on PAS (^#) and appearance of increase collagen on PSR (†).