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Effect of nitric oxide on β-adrenergic receptor-stimulated sarcomere shortening in WT and sGCα1−/− CM. Representative tracing demonstrating time-dependent change in sarcomere length of a single isoproterenol (ISO)-stimulated, paced WT (top) and sGCα1−/− (bottom) CM during perfusion with 100 μM spermine NONOate.
