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Hypercapnic ventilatory response/central chemoreceptor sensitivity (CCS; in l·min−1·Torr−1) averaged over all control subjects (left) and averaged over all POTS patients (right). Top: results during supine position. Bottom: results during HUT position. POTS patients have a decreased supine CCS compared with controls. Baroreflex unloading does not decrease the CCS in controls but decreases the CCS in POTS patients.
