Table 5.
Changes in overall quality of life.
| SF-36 component | APR 68 (44%) | LAR 85 (56%) | Nonadjusted analysis | Adjusted analysisb | ||
| Difference in meansa (95% CI) | p - Value | Difference in meansa (95% CI) | p Value | |||
| Physical | ||||||
| 6 mo | −1.7 ± 11.6N = 25 | −2.0 ± 9.5N = 48 | −0.4 (−5.4 to +4.6) | 0.88 | +0.4 (−5.1 to +5.9) | 0.89 |
| 12 mo | 1.0 ± 8.7N = 30 | −1.12 ± 9.7N = 55 | −2.2 (−6.4 to +2.1) | 0.32 | −1.3 (−5.9 to +3.3) | 0.58 |
| 36 mo | −2.2 ± 11.9N = 25 | −0.6 ± 9.5N = 29 | +1.7 (−4.1 to +7.4) | 0.57 | +3.2 (−3.1 to +9.4) | 0.33 |
| Mental | ||||||
| 6 mo | 0.6 ± 10.0N = 25 | −2.5 ± 11.4N = 48 | −3.1 (−8.4 to +2.2) | 0.26 | −3.1 (−9.1 to +2.9) | 0.31 |
| 12 mo | 4.4 ± 11.0N = 30 | −2.5 ± 10.3N = 55 | −6.9 (−11.7 to +2.2) | 0.005 | −7.9 (−13.1 to +2.6) | 0.004 |
| 36 mo | 2.5 ± 11.2N = 25 | −1.5 ± 11.1N = 29 | −4.0 (−10.0 to +2.0) | 0.2 | −4.2 (−10.7 to +2.3) | 0.21 |
Values expressed as means and standard deviation. SF-36: Short form, APR: Abdominoperienal resection, LAR: Low anterior resection, CI: Confidence interval.
A complete quality of life (QOL) follow-up could not be obtained for a portion of patients involved in this study. Changes in QOL calculated by subtracting the mean SF-36 score from the baseline mean SF-36 score. a Calculated by subtracting the changes in SF-36 score of LAR from change in SF-36 score of APR patients. b Analysis adjusted for age at surgery, pathologic stage, use of radiation therapy,and 30 d postoperative complications.