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. Author manuscript; available in PMC: 2011 Jul 5.
Published in final edited form as: Genes Brain Behav. 2010 Aug 12;9(7):817–824. doi: 10.1111/j.1601-183X.2010.00620.x

Figure 4. Acb injections of Lmo4 shRNA enhance locomotor responses to cocaine.

Figure 4

(a) Cocaine sensitization in mice expressing shLmo4.3 (triangles) or shScr (circles) in the Acb. Mice received either cocaine (open symbols) or saline (closed symbols) on days 3–7; all animals received cocaine on day 17. (b) Lentivirus infection in Acb as visualized by immunohistochemistry with an anti-GFP antibody (brown). Sections were also stained with cresyl violet to show cytoarchitecture. Infection generally spread 0.5 mm from the injection site. Lower panel shows a higher magnification view of GFP-positive neurons near the edge of the infection site. ac = anterior commissure; LV = lateral ventricle (c) Cocaine sensitization in mice expressing shLmo4.3 (open circles) and shScr (closed circles) in Cpu. No differences were observed between mice expressing shLmo4.3 or shScr.