Figure 3. Dorsal closure process is blocked in mutant heph embryos.

While in the wild type embryo the dorsal region was closed and the extra-embryonic amnioserosa (AS) was completely eliminated by about 22 hours after egg laying (left), in heph⁰³⁴²⁹ and heph² embryos the dorsal closure process was incomplete and AS persisted even after 48 hours. Embryos were labeled using the actin antibody. All embryos/larva shown were from the same experiment and were processed identically.