Table 5.
Univariate Analysis of Relationship Between the jhp0917–0918 and cag PAI Status and Histology
| No. | Antrum
|
Corpus
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| H pylori density | Neutrophil infiltration | Intestinal metaplasia | Atrophy | H pylori density | Neutrophil infiltration | Intestinal metaplasia | Atrophy | ||
| Japan | |||||||||
| jhp0917–0918 | |||||||||
| Positive | 34 | 3.0 (3) | 3.5 (3) | 0.4 (0) | 0.6 (0) | 2.6 (3) | 2.3 (3) | 0.3 (0) | 0.3 (0) |
| Negative | 124 | 2.7 (3) | 2.1 (2) | 1.1 (1) | 2.1 (2) | 2.1 (2) | 1.8 (2) | 1.0 (1) | 1.8 (1) |
| P value | .07 | <.001 | .006 | <.001 | NS | <.001 | .043 | <.001 | |
| Colombia | |||||||||
| jhp0917–0918 | |||||||||
| Positive | 50 | 2.5 (2) | 2.8 (3) | 0.2 (0) | 0.6 (0) | 2.4 (2) | 2.3 (2) | 0.1 (0) | 0.3 (0) |
| Negative | 87 | 2.2 (2) | 1.7 (2) | 1.1 (0) | 1.7 (1) | 2.2 (2) | 1.7 (2) | 1.0 (0) | 1.1 (0.5) |
| P value | NS | .002 | .004 | <.001 | NS | .023 | .003 | <.001 | |
| cag PAI | |||||||||
| Positive | 125 | 2.4 (2) | 2.5 (2) | 0.9 (0) | 1.4 (1) | 2.3 (2) | 2.0 (2) | 0.7 (0) | 0.9 (0) |
| Negative | 17 | 2.3 (2.5) | 1.6 (2) | 0.4 (0) | 0.5 (0) | 2.2 (2) | 1.3 (1) | 0.1 (0) | 0 (0) |
| P value | NS | .057 | NS | .037 | NS | .063 | NS | .009 | |
NOTE. For histologic scores (minimum 0 to maximum 5), mean (median) scores are presented. The cag PAI data in Japan did not show because there were no cag PAI negative strains in Japan. Other vir factors were not related to changes in gastric histology and were not shown.
NS, not significant; P > .10.