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. Author manuscript; available in PMC: 2011 Jul 5.
Published in final edited form as: J Biol Chem. 2007 Jan 3;282(9):6242–6254. doi: 10.1074/jbc.M611178200

FIGURE 4. IL-6 and IL-8 promoter activation following H.pylori infection.

FIGURE 4

Three independent transfections, each done in triplicate, were performed. Data are expressed as mean ± S.E. MKN28 cells were transiently transfected with 2 μg of plasmids containing various IL-6 and IL-8 promoters and 10 ng of Renilla plasmid as an internal control. The cells then infected with H. pylori for 9 h. Untreated cells served as controls. Normalized luciferase activity induced by H. pylori infection is expressed as -fold increase in H. pylori-infected cells over uninfected controls. *, p < 0.05; **,p < 0.01, compared with WT strains. †, p < 0.05;††, p < 0.01, compared with p162hu.IL8Luc or p1168hu.IL6Luc.