Skip to main content
. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Psychoneuroendocrinology. 2011 Mar 15;36(8):1164–1174. doi: 10.1016/j.psyneuen.2011.02.008

Figure 2. Effects of CIC stress on LPS-induced changes in pro-inflammatory cytokine expression in hypothalamus.

Figure 2

Rats were sacrificed 2h or 5h after LPS (0.2mg/kg, IP), or an equal volume of saline vehicle. Data from both time points in the vehicle-injected animals were pooled. Levels of IL1β protein (panel A, n= 11–15), IL1β mRNA (panel B, n= 8–10), IL6 mRNA (panel C, n= 7–10) and COX2 mRNA (panel D, 8–10) were measured in the hypothalamus. * significantly different from Vehicle control in the same treatment group; + significantly different comparing NS and CIC (Chronic Intermittent Cold) at the same time point; all comparisons by Newman-Keuls post-test at p<0.05.