Table 1.
Mass of either the testes or oviduct, plasma testosterone (T) concentration, and plasma estradiol (E2) concentration (± S.E.M.) for male and female zebra finches from mixed-sex housing. Subjects were treated with vehicle or Letrozole on a daily basis for three weeks. Subjects were also given subcutaneous implants that were either empty or filled with crystalline E2 for the duration of the study. Abbreviations: CTRL, vehicle plus empty implant; LET, Letrozole plus empty implant; LET+E2, Letrozole plus E2; N, group size. See text for statistical differences among groups. Adapted from Kabelik et al. [35].
Females | Males | |||||
---|---|---|---|---|---|---|
CTRL | LET | LET+E2 | CTRL | LET | LET+E2 | |
N | 6 | 5 | 3 | 6 | 5 | 6 |
testes or oviduct mass (g)* | 0.073 (0.024) | 0.023 (0.006) | 0.43 (0.08) | 0.048 (0.006) | 0.042 (0.005) | 0.003 (0.001) |
| ||||||
T (ng/ml)* | 0.033 (0.006) | 0.28 (0.040) | 0.016 (0.007) | 3.47 (0.67) | 3.84 (0.95) | 0.023 (0.004) |
| ||||||
E2 (ng/ml)* | 0.023 (0.003) | 0.030 (0.004) | 1.82 (0.14) | 0.033 (0.005) | 0.052 (0.010) | 0.99 (0.21) |
*Testes mass, p < 0.0001
*Oviduct mass, p < 0.0001
*T level, males vs. females, p < 0.0001
*T level, treatment effect, p < 0.0001; posthoc: LET > CTRL > LET+E2
*T level, sex*treatment, p < 0.0001; posthoc: ♂ LET = ♂ CTRL > ♀ LET > ♀ CTRL = ♂ LET+E2 = ♀ LET+E2
*E2 level, treatment effect, p < 0.0001; posthoc: LET+E2>CTRL=LET
*E2 level, sex*treatment, p = 0.007; posthoc: ♀ LET+E2 > ♂ LET+E2 > ♂ LET ≥ ♂ CTRL ≥ ♀ LET = ♀ CTRL