Figure 6.

All five light inputs are important for the function of the model.In each panel, the dynamics of CCA1–LUC are compared between the ‘wild-type’ model (blue lines) and mutated models in which one light input is disabled.(a–d) L:D 12:12 conditions; the rate constant governed by the examined light input is set equal to the value it takes in the light (red) or dark (green) in the wild-type model. (a) Degradation rate of CCA1. (b) TOC1-mediated transcription of CCA1. (c) Degradation rate of active TOC1. (d) TOC1 protein activation rate.(e) The function of the light accumulator (acc) is demonstrated across two photoperiod changes, with TOC1 transcription either made independent of the light by setting acc to 1 (grey), or modulated directly by the light, bypassing acc (purple). Experimental data (blue crosses) are included for comparison, and have been re-scaled as described in Experimental procedures.