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CTCAE grade ≥3 events reported by any patient
| Patients with grade ≥3 event, N (%) | |||||
|---|---|---|---|---|---|
| AZD4877 dose | |||||
| 10 mg (N = 3) | 15 mg (N = 3) | 20 mg (N = 6) | 25 mg (N = 6) | Total (N = 18) | |
| Any grade ≥3 event | 0 | 0 | 1 (17) | 2 (33) | 3 (17) |
| Febrile neutropenia | 0 | 0 | 0 | 1 (17) | 1 (6) |
| Neutropenia | 0 | 0 | 1 (17) | 0 | 1 (6) |
| Constipation | 0 | 0 | 0 | 1 (17) | 1 (6) |
| Fatigue | 0 | 0 | 0 | 1 (17) | 1 (6) |
| Urinary tract infection | 0 | 0 | 0 | 1 (17) | 1 (6) |
| Anorexia | 0 | 0 | 0 | 1 (17) | 1 (6) |
