The U2/U6/BS
crosslink contains U2/U6 helix II. (A and B) Unlabeled Adeno 5′ SS
and 32P-labeled Adeno 3′ RNA
were incubated in nuclear extract as in Figure 2A, and crosslinked
as in Figure 2B. RNA was then purified, subjected to RNase H cleavage
targeted by the indicated oligodeoxynucleotides, and the products
resolved by denaturing 5% PAGE. The positions of the U2/BS
and U2/U6/BS crosslinks, and the 3′ RNA
substrate, are indicated. (A) Left to right, lanes 1–7.
(B) Left to right, lanes 1–6.